The Napkin-Ring Sign: CT Signature of High-Risk Coronary Plaques?

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Coronary CT Angiography and the Napkin-ring Sign Indicates High-Risk Atherosclerotic Lesions

Coronary computed tomography angiography (CCTA) is used extensively nowa‐ days as a non-invasive imaging method for the evaluation of patients suspected of coronary artery disease, providing data on calcium burden, the presence of coro‐ nary artery stenoses, but also, more recently, on coronary atherosclerotic plaque morphology and composition. Plaque morphology analysis by CCTA aims to accu‐ r...

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Histopathological correlates of the napkin-ring sign plaque in coronary CT angiography.

OBJECTIVE The purpose of this study was to identify histologic characteristics of advanced coronary atherosclerotic plaques that are related with the detection of the napkin-ring sign (NRS) in coronary CT angiography (CCTA). METHODS CCTA was performed in 7 human donor hearts. Histological slicing and stainings were performed in 1 mm increments of each major coronary artery. Histology was co-r...

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The napkin-ring sign indicates advanced atherosclerotic lesions in coronary CT angiography.

OBJECTIVES This study sought to determine the accuracy of plaque pattern assessment by coronary computed tomography angiography (CCTA) to differentiate between early and advanced atherosclerotic lesions as defined by histology. BACKGROUND A ringlike attenuation pattern of coronary atherosclerotic plaques termed as napkin-ring sign (NRS) was described in CCTA of patients who had acute coronary...

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Radiomic Features Are Superior to Conventional Quantitative Computed Tomographic Metrics to Identify Coronary Plaques With Napkin-Ring Sign

BACKGROUND Napkin-ring sign (NRS) is an independent prognostic imaging marker of major adverse cardiac events. However, identification of NRS is challenging because of its qualitative nature. Radiomics is the process of extracting thousands of quantitative parameters from medical images to create big-data data sets that can identify distinct patterns in radiological images. Therefore, we sought...

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Novel CT-based imaging markers for high-risk coronary plaques.

A large proportion of patients with suspected coronary artery disease who are referred for coronary computed tomography angiography (CTA) have coronary atherosclerotic lesions that do not cause significant anatomical luminal obstruction. These nonobstructive coronary artery lesions provide incremental prognostic information over the presence of obstructive lesions and clinical variables. 5 Howe...

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ژورنال

عنوان ژورنال: JACC: Cardiovascular Imaging

سال: 2010

ISSN: 1936-878X

DOI: 10.1016/j.jcmg.2010.02.003